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Antimicrobial Agents and Chemotherapy, June 2005, p. 2525-2527, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2525-2527.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Multicenter Study of the Mechanisms of Resistance and Clonal Relationships of Streptococcus agalactiae Isolates Resistant to Macrolides, Lincosamides, and Ketolides in Spain

J. J. Gonzalez, A. Andreu,* the Spanish Group for the Study of Perinatal Infection from the Spanish Society for Clinical Microbiology and Infectious Diseases,{dagger}

Servicio de Microbiologia, Hospital Vall d'Hebron, 08035 Barcelona, Spain

Received 26 November 2004/ Returned for modification 20 December 2004/ Accepted 22 February 2005

Macrolide, lincosamide, and ketolide mechanisms of resistance and clonal relationships were characterized in a collection of 79 resistant group B streptococcus isolates obtained from neonates or pregnant women. The erm(B), erm(TR), and mef(A) genes were present in 62%, 30.4%, and 3.8% of the isolates, respectively. There was considerable clonal diversity among them.

* Corresponding author. Mailing address: Servicio de Microbiología, Hospital Vall d'Hebron, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. Phone: 34-93-274 6867. Fax: 34-93-274 6801. E-mail: anandreu{at}vhebron.net.

{dagger} Contributing members of the Spanish Group for the Study of Perinatal Infection from the Spanish Society for Clinical Microbiology and Infectious Diseases are listed in Acknowledgments.

Antimicrobial Agents and Chemotherapy, June 2005, p. 2525-2527, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2525-2527.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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