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Antimicrobial Agents and Chemotherapy, June 2005, p. 2539-2540, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2539-2540.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of Amphotericin B and Voriconazole against Aleurioconidia from Aspergillus terreus

Cornelia Lass-Flörl,* Alexandra Rief, Sandra Leitner, Cornelia Speth, Reinhard Würzner, and Manfred P. Dierich

Department of Hygiene, Microbiology and Social Medicine, Medical University Innsbruck, Innsbruck, Austria

Received 10 November 2004/ Returned for modification 5 January 2005/ Accepted 21 February 2005

This study used aleurioconidia as inoculum and compared the MICs of amphotericin B and voriconazole to those obtained for conidia of 31 Aspergillus terreus strains. For conidia and aleurioconidia, the MIC at which 90% of strains were inhibited was 2.5 µg/ml and 5 µg/ml with amphotericin B and 1 µg/ml and 2 µg/ml with voriconazole.

* Corresponding author. Mailing address: Department of Hygiene, Microbiology and Social Medicine, Medical University Innsbruck, Fritz Pregl Str. 3/III, Innsbruck 6020, Austria. Phone: 43-512-507-3425. Fax: 43-512-507-2870. E-mail: Cornelia.Lass-Floerl{at}uibk.ac.at.

Antimicrobial Agents and Chemotherapy, June 2005, p. 2539-2540, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2539-2540.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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