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Antimicrobial Agents and Chemotherapy, June 2005, p. 2565-2567, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2565-2567.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Chromosome-Borne Class A BOR-1 ß-Lactamase of Bordetella bronchiseptica and Bordetella parapertussis

Marie-Frédérique Lartigue, Laurent Poirel, Nicolas Fortineau, and Patrice Nordmann*

Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université Paris XI, 94275 K.-Bicêtre, France

Received 8 November 2004/ Returned for modification 12 December 2004/ Accepted 15 February 2005

A narrow-spectrum clavulanic acid-inhibited class A ß-lactamase, BOR-1, was identified in a Bordetella bronchiseptica clinical isolate. It shared 45% amino acid identity with L-2 from Stenotrophomonas maltophilia. An identical ß-lactamase gene was found in B. bronchiseptica and Bordetella parapertussis reference strains that may contribute only in part to their resistance phenotype.

* Corresponding author. Mailing address: Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 K.-Bicêtre, France. Phone: 33-1-45-21-36-32. Fax: 33-1-45-21-63-40. E-mail: nordmann.patrice{at}bct.ap-hop-paris.fr.

Antimicrobial Agents and Chemotherapy, June 2005, p. 2565-2567, Vol. 49, No. 6
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.6.2565-2567.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kadlec, K., Wiegand, I., Kehrenberg, C., Schwarz, S. (2007). Studies on the mechanisms of {beta}-lactam resistance in Bordetella bronchiseptica. J Antimicrob Chemother 59: 396-402 [Abstract] [Full Text]  
  • Jacoby, G. A. (2006). {beta}-Lactamase Nomenclature.. Antimicrob. Agents Chemother. 50: 1123-1129 [Full Text]  


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