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Antimicrobial Agents and Chemotherapy, August 2005, p. 3566-3568, Vol. 49, No. 8
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.8.3566-3568.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Effect of Various Antibacterial Preparations on the Pathogenic Oral Flora in Elderly Patients Fed via Nasogastric Tube

Arthur Leibovitz,* Yehuda Carmeli, and Refael Segal

Shmuel-Harofeh, Geriatric Medical Center, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

Received 26 February 2005/ Returned for modification 27 March 2005/ Accepted 26 April 2005

Oropharyngeal colonization by pathogenic gram-negative bacilli (GNB) and Staphylococcus aureus is associated with aspiration pneumonia. Decolonization in high-risk populations may be important. We prospectively evaluated six antiseptic compounds in nasogastric tube-fed frail elderly patients; only polymixine reduced oropharyngeal colonization with GNB. None had an effect on S. aureus colonization.

* Corresponding author. Mailing address: Shmuel-Harofeh Hospital, Geriatric Medical Center, POB 2, Be'er-Ya'akov, 70350, Israel. Phone: 972 89258622. Fax: 972 89237156. E-mail: shmuelh{at}netvision.net.il.

Antimicrobial Agents and Chemotherapy, August 2005, p. 3566-3568, Vol. 49, No. 8
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.8.3566-3568.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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