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Antimicrobial Agents and Chemotherapy, September 2005, p. 3940-3943, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3940-3943.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Chromosome- and Plasmid-Encoded ß-Lactamases in Capnocytophaga spp.

Trude Handal,1* Chantal Giraud-Morin,2 Dominique A. Caugant,1,3 Isabelle Madinier,2 Ingar Olsen,1 and Thierry Fosse2

Department of Oral Biology, Dental Faculty, University of Oslo, Oslo, Norway,1 Laboratoire Mixte Médecine-Odontologie, Ecologie Microbienne et Résistance aux Antibiotiques, Hopital L'Archet 2, Centre Hospitalier Universitaire de Nice, Nice, France,2 Department of Airborne Infections, Norwegian Institute of Public Health, Oslo, Norway3

Received 10 January 2005/ Returned for modification 7 April 2005/ Accepted 5 July 2005

Chromosome- and plasmid-encoded CfxA2 and CfxA3 ß-lactamases were detected in Capnocytophaga spp. from oral sources in France, Norway, and the United States. Unidentified chromosome-encoded ß-lactamases were present in Capnocytophaga sputigena. Nucleotide sequence analysis of the CfxA3-encoding plasmid from C. ochracea revealed an unreported insertion sequence (ISCoc1) upstream of the cfxA gene.

* Corresponding author. Mailing address: Department of Oral Biology, Dental Faculty, University of Oslo, P.O. Box 1052 Blindern, 0316 Oslo, Norway. Phone: (47) 22840327. Fax: (47) 22840305. E-mail: thandal{at}odont.uio.no.

Antimicrobial Agents and Chemotherapy, September 2005, p. 3940-3943, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3940-3943.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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