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Antimicrobial Agents and Chemotherapy, September 2005, p. 3952-3954, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3952-3954.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

In Vitro Antifungal Susceptibilities of Sporothrix schenckii in Two Growth Phases

Luciana Trilles,1 Belkys Fernández-Torres,2 Márcia dos Santos Lazéra,1 Bodo Wanke,1 Armando de Oliveira Schubach,1 Rodrigo de Almeida Paes,1 Isabel Inza,2 and Josep Guarro2*

Serviço de Micologia Médica, Instituto de Pesquisa Clínica Evandro Chagas, FIOCRUZ, Rio de Janeiro, Brazil,1 Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain2

Received 28 December 2004/ Returned for modification 5 January 2005/ Accepted 5 June 2005

We have determined the antifungal susceptibilities of 34 clinical isolates of the dimorphic fungus Sporothrix schenckii to 11 drugs using a microdilution method. In general, the type of growth phase (mycelial or yeast) and the temperature of incubation (30 or 35°C) exerted a significant influence on the MICs.


* Corresponding author. Mailing address: Unitat de Microbiología, Facultat de Medicina, Universitat Rovira i Virgili, Carrer Sant Llorenç, 21, 43201 Reus, Spain. Phone: 34-977-759359. Fax: 34-977-759322. E-mail: josep.guarro{at}urv.net.


Antimicrobial Agents and Chemotherapy, September 2005, p. 3952-3954, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3952-3954.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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  • Marimon, R., Serena, C., Gene, J., Cano, J., Guarro, J. (2008). In Vitro Antifungal Susceptibilities of Five Species of Sporothrix. Antimicrob. Agents Chemother. 52: 732-734 [Abstract] [Full Text]  
  • Marimon, R., Cano, J., Gene, J., Sutton, D. A., Kawasaki, M., Guarro, J. (2007). Sporothrix brasiliensis, S. globosa, and S. mexicana, Three New Sporothrix Species of Clinical Interest. J. Clin. Microbiol. 45: 3198-3206 [Abstract] [Full Text]