AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ríos, A. M.
Right arrow Articles by Hardy, R. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ríos, A. M.
Right arrow Articles by Hardy, R. D.
Antimicrobial Agents and Chemotherapy, September 2005, p. 3970-3973, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3970-3973.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Microbiologic and Immunologic Evaluation of a Single High Dose of Azithromycin for Treatment of Experimental Mycoplasma pneumoniae Pneumonia

Ana María Ríos, Mónica Fonseca-Aten, Asunción Mejías, Susana Chávez-Bueno, Kathy Katz, Ana María Gómez, George H. McCracken Jr., Octavio Ramilo, and R. Doug Hardy*

Department of Pediatrics, Internal Medicine, and Pathology, University of Texas Southwestern Medical Center, Dallas, Texas

Received 25 February 2005/ Returned for modification 15 May 2005/ Accepted 21 June 2005

We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.

* Corresponding author. Mailing address: Department of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9063. Phone: (214) 648-3720. Fax: (214) 648-2961. E-mail: robert.hardy{at}utsouthwestern.edu.

Antimicrobial Agents and Chemotherapy, September 2005, p. 3970-3973, Vol. 49, No. 9
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.9.3970-3973.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 2005 by the American Society for Microbiology. All rights reserved.