This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Baker, C. N.
Right arrow Articles by Thornsberry, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Baker, C. N.
Right arrow Articles by Thornsberry, C.

 Previous Article  |  Next Article 

Antimicrob Agents Chemother. 1974 March; 5(3): 268-271
Copyright © 1974 American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibility of Streptococcus mutans Isolated from Patients with Endocarditis

Carolyn N. Baker and Clyde Thornsberry

Center for Disease Control, Atlanta, Georgia 30333

ABSTRACT

Forty-one strains of Streptococcus mutans (34 from blood specimens from patients with endocarditis and 7 from stock cultures) were tested for susceptibility to penicillin, ampicillin, methicillin, erythromycin, cephalothin, vancomycin, chloramphenicol, tetracycline, gentamicin, streptomycin, and kanamycin. Minimal inhibitory and bactericidal concentrations were determined by a broth microdilution procedure. Most of the strains were very susceptible to ampicillin, penicillin, and erythromycin, with most strains having minimal inhibitory concentrations of 0.08 µg/ml or less. Most of the strains were also susceptible to cephalothin, methicillin, chloramphenicol, tetracycline, and vancomycin. Gentamicin was the most effective aminoglycoside. The antimicrobial susceptibility patterns are similar to those of other viridans streptococci. S. mutans strains have proven to be difficult for some microbiologists to identify. But when organisms suggesting S. mutans are isolated from patients with endocarditis, they should be at least identified as nonenterococcal streptococci so that appropriate therapy can be initiated.

Antimicrob Agents Chemother. 1974 March; 5(3): 268-271
Copyright © 1974 American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Sweeney, L. C., Dave, J., Chambers, P. A., Heritage, J. (2004). Antibiotic resistance in general dental practice--a cause for concern?. J Antimicrob Chemother 53: 567-576 [Abstract] [Full Text]  
  • Leistevuo, J., Järvinen, H., Österblad, M., Leistevuo, T., Huovinen, P., Tenovuo, J. (2000). Resistance to Mercury and Antimicrobial Agents in Streptococcus mutans Isolates from Human Subjects in Relation to Exposure to Dental Amalgam Fillings. Antimicrob. Agents Chemother. 44: 456-457 [Abstract] [Full Text]  
  • Balanyk, T.E., Sandham, H.J. (1985). Development of Sustained-release Antimicrobial Dental Varnishes Effective Against Streptococcus mutans in vitro. JDR 64: 1356-1360 [Abstract]  
  • Maltz, M., Emilson, C.G. (1982). Susceptibility of Oral Bacteria to Various Fluoride Salts. JDR 61: 786-790 [Abstract]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»