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Antimicrobial Agents and Chemotherapy, October 2006, p. 3476-3478, Vol. 50, No. 10
0066-4804/06/$08.00+0     doi:10.1128/AAC.00402-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Intrinsic Macrolide Resistance in Rapidly Growing Mycobacteria{dagger}

Kevin A. Nash,1* Nadya Andini,1 Yansheng Zhang,2 Barbara A. Brown-Elliott,2 and Richard J. Wallace Jr.2

Department of Pathology, University of Southern California, and Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, California,1 Department of Microbiology, The University of Texas Health Center at Tyler, Tyler, Texas2

Received 31 March 2006/ Returned for modification 17 May 2006/ Accepted 14 July 2006

This study reports the discovery of erm genes in seven species of rapidly growing mycobacteria (RGM): Mycobacterium boenickei, M. goodii, M. houstonense, M. mageritense, M. neworleansense, M. porcinum, and M. wolinskyi. This study further substantiates the role of erm genes in intrinsic macrolide resistance in RGM.


* Corresponding author. Mailing address: Department of Pathology and Laboratory Medicine, Saban Research Institute of Childrens Hospital Los Angeles, 4650 Sunset Blvd., Mailstop 103, Los Angeles, CA 90027. Phone: (323) 669-5670. Fax: (323) 666-7681. E-mail: kanash{at}usc.edu.

{dagger} Supplemental material for this article may be found at http://aac.asm.org/.


Antimicrobial Agents and Chemotherapy, October 2006, p. 3476-3478, Vol. 50, No. 10
0066-4804/06/$08.00+0     doi:10.1128/AAC.00402-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.







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