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Antimicrobial Agents and Chemotherapy, November 2006, p. 3929-3933, Vol. 50, No. 11
0066-4804/06/$08.00+0     doi:10.1128/AAC.00569-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Complete DNA Sequence, Comparative Genomics, and Prevalence of an IncHI2 Plasmid Occurring among Extraintestinal Pathogenic Escherichia coli Isolates {triangledown},{dagger}

Timothy J. Johnson, Yvonne M. Wannemeuhler, Jennifer A. Scaccianoce, Sara J. Johnson, and Lisa K. Nolan*

Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, 1802 Elwood Drive, VMRI 2, Iowa State University, Ames, Iowa 50011

Received 8 May 2006/ Returned for modification 6 July 2006/ Accepted 14 August 2006

We have sequenced a large plasmid that occurs among avian pathogenic Escherichia coli isolates. This plasmid, pAPEC-O1-R, is a 241,387-bp IncHI2 plasmid which is cotransmissible via bacterial conjugation with a ColBM virulence plasmid, encodes resistance to eight antimicrobial agents, and appears to occur at low rates among extraintestinal E. coli isolates.


* Corresponding author. Mailing address: Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, 1802 Elwood Drive, VMRI 2, Iowa State University, Ames, IA 50011. Phone: (515) 294-3470. Fax: (515) 294-3839. E-mail: lknolan{at}iastate.edu.

{dagger} Supplemental material for this article may be found at http://aac.asm.org/.

{triangledown} Published ahead of print on 28 August 2006.


Antimicrobial Agents and Chemotherapy, November 2006, p. 3929-3933, Vol. 50, No. 11
0066-4804/06/$08.00+0     doi:10.1128/AAC.00569-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.




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