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Hershey Medical Center, Hershey, Pennsylvania 17033,1 JMI Laboratories, North Liberty, Iowa 523172
Received 1 September 2006/ Returned for modification 19 September 2006/ Accepted 19 September 2006
Against 198 viridans group streptococci, 25 Streptococcus bovis strains, and 5 Cardiobacterium hominis strains, MICs of DX-619, a des-F(6)-quinolone, were between 0.004 and 0.25 µg/ml. These MICs were lower than those of other quinolones (
0.008 to >32 µg/ml). ß-Lactam MICs were between
0.008 and 16 µg/ml. Azithromycin resistance was found in most species, while most were telithromycin susceptible. Glycopeptides and linezolid were active against viridans group strains but inactive against C. hominis.
Published ahead of print on 16 October 2006.
| Clin. Vaccine Immunol. | Clin. Microbiol. Rev. |
|---|---|
| J. Clin. Microbiol. | ALL ASM JOURNALS |