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Antimicrobial Agents and Chemotherapy, December 2006, p. 4209-4210, Vol. 50, No. 12
0066-4804/06/$08.00+0     doi:10.1128/AAC.00814-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Prevalence of Trichomonas vaginalis Isolates with Resistance to Metronidazole and Tinidazole{triangledown}

Jane R. Schwebke* and Frank J. Barrientes

Department of Medicine, University of Alabama at Birmingham, ZRB 239, 1530 3rd Ave. S., Birmingham, Alabama 35294-0007

Received 21 June 2006/ Returned for modification 1 September 2006/ Accepted 17 September 2006

Clinical isolates of Trichomonas vaginalis were obtained from women consecutively enrolled in a study of partner notification. Testing of susceptibility to metronidazole and tinidazole was performed. Resistance to metronidazole and tinidazole was present in 17/178 (9.6%) and 1/178 (0.56%) strains, respectively. In vitro resistance was poorly correlated with clinical response to treatment.

* Corresponding author. Mailing address: University of Alabama at Birmingham, ZRB 239, 1530 3rd Ave. S., Birmingham, AL 35294-0007. Phone: (205) 975-5665. Fax: (205) 975-7764. E-mail: schwebke{at}uab.edu.

{triangledown} Published ahead of print on 25 September 2006.

Antimicrobial Agents and Chemotherapy, December 2006, p. 4209-4210, Vol. 50, No. 12
0066-4804/06/$08.00+0     doi:10.1128/AAC.00814-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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