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Antimicrobial Agents and Chemotherapy, February 2006, p. 756-758, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.756-758.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Occurrence of OXA-58-Like Carbapenemases in Acinetobacter spp. Collected over 10 Years in Three Continents

Juliana Coelho,{dagger} Neil Woodford, Mariya Afzal-Shah,{ddagger} and David Livermore*

Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, United Kingdom

Received 20 September 2005/ Returned for modification 24 October 2005/ Accepted 30 October 2005

OXA-58 is a recently described carbapenemase from Acinetobacter spp. in Europe. We examined earlier worldwide Acinetobacter collections and found blaOXA-58 in 30 carbapenem-nonsusceptible isolates, including several isolates collected in Argentina and Kuwait in 1995 and 1996 and in a British outbreak strain from 2000. Most isolates (28 of 30) also had blaOXA-51. We conclude that blaOXA-58 is geographically widespread and has occurred in Acinetobacter spp. for over 10 years.

* Corresponding author. Mailing address: Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5HT, United Kingdom. Phone: 44-(0)20-8327-7223. Fax: 44-(0)20-8327-6264. E-mail: david.livermore{at}hpa.org.uk.

{dagger} Present address: National Bacteriology Laboratory, National Blood Service, Colindale Avenue, Colindale, London NW9 5BG, United Kingdom.

{ddagger} Present address: GR Micro, 7-9 William Road, London NW1 3ER, United Kingdom.

Antimicrobial Agents and Chemotherapy, February 2006, p. 756-758, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.756-758.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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