AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vignoli, R.
Right arrow Articles by Ayala, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vignoli, R.
Right arrow Articles by Ayala, J. A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, February 2006, p. 781-784, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.781-784.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

New TEM-Derived Extended-Spectrum ß-Lactamase and Its Genomic Context in Plasmids from Salmonella enterica Serovar Derby Isolates from Uruguay

Rafael Vignoli,1 Nicolas F. Cordeiro,1 Virginia García,1 María Inés Mota,1 Laura Betancor,2 Pablo Power,3 José A. Chabalgoity,2 Felipe Schelotto,1 Gabriel Gutkind,3 and Juan A. Ayala4*

Departamento de Bacteriología y Virología,1 Departamento de Biotecnología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, 11600 Montevideo, Uruguay,2 Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 1113 Buenos Aires, Argentina,3 Centro de Biología Molecular "Severo Ochoa," CSIC-UAM, Campus de Cantoblanco, 28049 Madrid, Spain4

Received 29 July 2005/ Returned for modification 1 September 2005/ Accepted 4 November 2005

A small (8.2-kb) ColE1 plasmid encoding TEM-144 (a new ß-lactamase with a ceftazidimase profile) was sequenced by a gene-walking strategy. The blaTEM allele was carried on a Tn2 element, disrupting a Rom protein gene. TEM-144 differs from TEM-1 by two mutations (R164C and E240K) and from the ceftazidime-hydrolyzing TEM-91 by one mutation (T182M).

* Corresponding author. Mailing address: Centro de Biología Molecular "Severo Ochoa," CSIC-UAM, Campus de Cantoblanco, 28049 Madrid, Spain. Phone: 34-91-4978083. Fax: 34-91-4978087. E-mail: jayala{at}cbm.uam.es.

Antimicrobial Agents and Chemotherapy, February 2006, p. 781-784, Vol. 50, No. 2
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.2.781-784.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 2006 by the American Society for Microbiology. All rights reserved.