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Antimicrobial Agents and Chemotherapy, March 2006, p. 1071-1074, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1071-1074.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Medium Plays a Role in Determining Expression of acrB, marA, and soxS in Escherichia coli

Andrew M. Bailey, Mark A. Webber, and Laura J. V. Piddock*

Antimicrobial Agents Research Group, Division of Immunity and Infection, The Medical School, The University of Birmingham, Birmingham B15 2TT, United Kingdom

Received 9 September 2005/ Returned for modification 12 October 2005/ Accepted 21 December 2005

Analysis of expression of acrB, marA, and soxS in rich and minimal media, at early and late logarithmic growth phases, showed that acrB had increased expression in minimal medium compared to rich medium, but expression decreased dose dependently upon exposure to ciprofloxacin.

* Corresponding author. Mailing address: Antimicrobial Agents Research Group, Division of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom. Phone: (44) 121-414-6966. Fax: (44) 121-414-6815. E-mail: l.j.v.piddock{at}bham.ac.uk.

Antimicrobial Agents and Chemotherapy, March 2006, p. 1071-1074, Vol. 50, No. 3
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.3.1071-1074.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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