This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Huys, G. Articles by Swings, J. Search for Related Content PubMed PubMed Citation Articles by Huys, G. Articles by Swings, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, April 2006, p. 1550-1551, Vol. 50, No. 4
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.4.1550-1551.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Genetic Basis of Tetracycline and Minocycline Resistance in Potentially Probiotic Lactobacillus plantarum Strain CCUG 43738

Laboratory of Microbiology,¹ BCCM/LMG Bacteria CollectionGhent University, K. L. Ledeganckstraat 35, B-9000 Ghent, Belgium²

Received 7 October 2005/ Returned for modification 2 November 2005/ Accepted 18 January 2006

The potentially probiotic strain Lactobacillus plantarum CCUG 43738, which displayed atypical phenotypic resistance to tetracycline (MIC, 512 µg/ml) and minocycline (MIC, 256 µg/ml), was found to contain a tet(S) gene located on a plasmid of approximately 14 kb. Plasmid curing with novobiocin eliminated this plasmid and restored the tetracycline-susceptible phenotype of the host strain.

This article has been cited by other articles:

• Ammor, M. S., Gueimonde, M., Danielsen, M., Zagorec, M., van Hoek, A. H. A. M., de los Reyes-Gavilan, C. G., Mayo, B., Margolles, A. (2008). Two Different Tetracycline Resistance Mechanisms, Plasmid-Carried tet(L) and Chromosomally Located Transposon-Associated tet(M), Coexist in Lactobacillus sakei Rits 9. Appl. Environ. Microbiol. 74: 1394-1401 [Abstract] [Full Text]  
• Klare, I., Konstabel, C., Werner, G., Huys, G., Vankerckhoven, V., Kahlmeter, G., Hildebrandt, B., Muller-Bertling, S., Witte, W., Goossens, H. (2007). Antimicrobial susceptibilities of Lactobacillus, Pediococcus and Lactococcus human isolates and cultures intended for probiotic or nutritional use. J Antimicrob Chemother 59: 900-912 [Abstract] [Full Text]