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Antimicrobial Agents and Chemotherapy, April 2006, p. 1555-1557, Vol. 50, No. 4
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.4.1555-1557.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

In Vitro Activity of Tigecycline against Burkholderia pseudomallei and Burkholderia thailandensis

Visanu Thamlikitkul* and Suwanna Trakulsomboon

Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand

Received 23 August 2005/ Returned for modification 31 October 2005/ Accepted 10 January 2006

Investigation of the in vitro activity of tigecycline against Burkholderia pseudomallei and Burkholderia thailandensis revealed that the inhibition zone diameters of tigecycline against all isolates were ≥20 mm and that the MIC50 values were 0.5 and 1 µg/ml and the MIC90 values were 2 and 1.5 µg/ml for B. pseudomallei and B. thailandensis, respectively.

* Corresponding author. Mailing address: Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. Phone: 662-412-5994. Fax: 662-412-5994. E-mail: sivth{at}mahidol.ac.th.

Antimicrobial Agents and Chemotherapy, April 2006, p. 1555-1557, Vol. 50, No. 4
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.4.1555-1557.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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