Previous Article | Next Article 
Antimicrobial Agents and Chemotherapy, May 2006, p. 1855-1858, Vol. 50, No. 5
0066-4804/06/$08.00+0 doi:10.1128/AAC.50.5.1855-1858.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Streptococcus pneumoniae Isolates Resistant to Telithromycin
M. Rantala,1,2*
M. Haanperä-Heikkinen,1
M. Lindgren,1
H. Seppälä,1,3
P. Huovinen,1
J. Jalava,1 and
the Finnish Study Group for Antimicrobial Resistance
Department of Bacteriology and Inflammation, National Public Health Institute, Turku, Finland,1
Department of Clinical Veterinary Sciences, Faculty of Veterinary Medicine, Helsinki University, Helsinki, Finland,2
Department of Ophthalmology, Turku City Hospital, Turku, Finland3
Received 20 December 2005/
Returned for modification 22 January 2006/
Accepted 6 March 2006
The telithromycin susceptibility of 210 erythromycin-resistant pneumococci was tested with the agar diffusion method. Twenty-six erm(B)-positive isolates showed heterogeneous resistance to telithromycin, which was manifested by the presence of colonies inside the inhibition zone. When these cells were cultured and tested, they showed stable, homogeneous, and high-level resistance to telithromycin.
* Corresponding author. Mailing address: Laboratory of Human Microbial Ecology, National Public Health Institute, Kiinamyllynkatu 13, FIN-20520 Turku, Finland. Phone: 358-2-331 6629. Fax: 358-2-331 6699. E-mail:
merja.rantala{at}ktl.fi.
Antimicrobial Agents and Chemotherapy, May 2006, p. 1855-1858, Vol. 50, No. 5
0066-4804/06/$08.00+0 doi:10.1128/AAC.50.5.1855-1858.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
This article has been cited by other articles:
-
Siira, L., Rantala, M., Jalava, J., Hakanen, A. J., Huovinen, P., Kaijalainen, T., Lyytikainen, O., Virolainen, A.
(2009). Temporal Trends of Antimicrobial Resistance and Clonality of Invasive Streptococcus pneumoniae Isolates in Finland, 2002 to 2006. Antimicrob. Agents Chemother.
53: 2066-2073
[Abstract]
[Full Text]
-
Rantala, M., Nyberg, S., Lindgren, M., Huovinen, P., Jalava, J., Skytta, R., Teirila, L., Vainio, A., Virolainen-Julkunen, A., Kaijalainen, T.
(2007). Molecular Epidemiology of Telithromycin-Resistant Pneumococci in Finland. Antimicrob. Agents Chemother.
51: 1885-1887
[Full Text]
-
Al-Lahham, A., Appelbaum, P. C., van der Linden, M., Reinert, R. R.
(2006). Telithromycin-Nonsusceptible Clinical Isolates of Streptococcus pneumoniae from Europe. Antimicrob. Agents Chemother.
50: 3897-3900
[Abstract]
[Full Text]