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Antimicrobial Agents and Chemotherapy, May 2006, p. 1887-1889, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1887-1889.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of DX-619 and Four Comparator Agents against 376 Anaerobic Bacterial Isolates

D. Molitoris,2 M.-L. Väisänen,2 M. Bolaños,2,{dagger} and S. M. Finegold1,2,3,4*

Medical,1 Research Services, VA Greater Los Angeles Healthcare System,2 Departments of Medicine,3 Microbiology, Immunology and Molecular Genetics, UCLA School of Medicine, Los Angeles, California4

Received 3 October 2005/ Returned for modification 29 October 2005/ Accepted 9 March 2006

The activity of DX-619 was evaluated against 376 anaerobic isolates using the reference CLSI agar dilution method. Overall, 90% of the strains were susceptible to DX-619 at ≤1 µg/ml. It was more active than the other four compounds tested except for meropenem, which showed virtually identical overall activity.

* Corresponding author. Mailing address: Greater Los Angeles VAMC, 11301 Wilshire Blvd., Bldg. 304, Rm. E3-237, Los Angeles, CA 90073. Phone: (310) 268-3678. Fax: (310) 268-4458. E-mail: sidfinegol{at}aol.com.

{dagger} Present address: Monseñor Sanabria Hospital, Puntarenas, Costa Rica.

Antimicrobial Agents and Chemotherapy, May 2006, p. 1887-1889, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1887-1889.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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