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Antimicrobial Agents and Chemotherapy, May 2006, p. 1887-1889, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1887-1889.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of DX-619 and Four Comparator Agents against 376 Anaerobic Bacterial Isolates

D. Molitoris,² M.-L. Väisänen,² M. Bolaños,^2, and S. M. Finegold^1,2,3,4*

Medical,¹ Research Services, VA Greater Los Angeles Healthcare System,² Departments of Medicine,³ Microbiology, Immunology and Molecular Genetics, UCLA School of Medicine, Los Angeles, California⁴

Received 3 October 2005/ Returned for modification 29 October 2005/ Accepted 9 March 2006

The activity of DX-619 was evaluated against 376 anaerobic isolates using the reference CLSI agar dilution method. Overall, 90% of the strains were susceptible to DX-619 at 1 µg/ml. It was more active than the other four compounds tested except for meropenem, which showed virtually identical overall activity.

Present address: Monseñor Sanabria Hospital, Puntarenas, Costa Rica.

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