This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Aspevall, O. Articles by Svenungsson, B. Search for Related Content PubMed PubMed Citation Articles by Aspevall, O. Articles by Svenungsson, B.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, May 2006, p. 1890-1892, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1890-1892.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibility Pattern of Clostridium difficile and Its Relation to PCR Ribotypes in a Swedish University Hospital

Department of Laboratory Medicine, Division of Clinical Bacteriology,¹ Department of Medicine, Division of Infectious Diseases, Karolinska University Hospital at Huddinge, Stockholm, Sweden,⁴ Department of Clinical Microbiology, Akademiska University Hospital, SE-751 85, Uppsala, Sweden,² Department of Bacteriology, Swedish Institute for Infectious Disease Control, Stockholm, Sweden,³ Department of Communicable Disease Control and Prevention, Karolinska University Hospital, Stockholm, Sweden⁵

Received 30 June 2005/ Returned for modification 12 October 2005/ Accepted 13 February 2006

All 238 Clostridium difficile isolates were susceptible to metronidazole and vancomycin, whereas 84% and 1% were resistant to clindamycin and fusidic acid. Etest MICs for metronidazole were lower than agar dilution MICs (P < 0.01) but without difference in susceptible-intermediate-resistant categorization. No particular PCR ribotype was associated with clindamycin or fusidic acid resistance.

This article has been cited by other articles:

• Labbe, A.-C., Poirier, L., MacCannell, D., Louie, T., Savoie, M., Beliveau, C., Laverdiere, M., Pepin, J. (2008). Clostridium difficile Infections in a Canadian Tertiary Care Hospital before and during a Regional Epidemic Associated with the BI/NAP1/027 Strain. Antimicrob. Agents Chemother. 52: 3180-3187 [Abstract] [Full Text]  
• Baines, S. D., O'Connor, R., Freeman, J., Fawley, W. N., Harmanus, C., Mastrantonio, P., Kuijper, E. J., Wilcox, M. H. (2008). Emergence of reduced susceptibility to metronidazole in Clostridium difficile. J Antimicrob Chemother 0: dkn313v1-7 [Abstract] [Full Text]  
• Halsey, J. (2008). Current and future treatment modalities for Clostridium difficile-associated disease. Am J Health Syst Pharm 65: 705-715 [Abstract] [Full Text]  
• Mutlu, E., Wroe, A. J., Sanchez-Hurtado, K., Brazier, J. S., Poxton, I. R. (2007). Molecular characterization and antimicrobial susceptibility patterns of Clostridium difficile strains isolated from hospitals in south-east Scotland. J Med Microbiol 56: 921-929 [Abstract] [Full Text]