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Antimicrobial Agents and Chemotherapy, May 2006, p. 1903-1907, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1903-1907.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Vibrio cholerae InV117, a Class 1 Integron Harboring aac(6')-Ib and blaCTX-M-2, Is Linked to Transposition Genes

Alfonso J. C. Soler Bistué,1,{dagger} Fernando A. Martín,1,{dagger} Alejandro Petroni,2 Diego Faccone,2 Marcelo Galas,2 Marcelo E. Tolmasky,3* and Angeles Zorreguieta1

Fundación Instituto Leloir, CONICET, and Inst. de Investigaciones Bioquímicas, FCEyN, University of Buenos Aires, Patricias Argentinas 435, C1405BWE Buenos Aires, Argentina,1 Serv. Antimicrobianos, INEI-ANLIS "Dr. Carlos G. Malbrán," Buenos Aires, Argentina,2 California State University Fullerton, Fullerton, California 92834-68503

Received 12 December 2005/ Returned for modification 16 February 2006/ Accepted 3 March 2006

A ca. 150-kbp Vibrio cholerae O1 biotype El Tor plasmid includes blaCTX-M-2 and a variant of aac(6')-Ib within InV117, an orf513-bearing class 1 integron. InV117 is linked to a tnp1696 module in which IRl carries an insertion of IS4321R. The complete structure could be a potential mobile element.

* Corresponding author. Mailing address: Department of Biological Science, California State University Fullerton, Fullerton, CA 92834-6850. Phone: (714) 278-5263. E-mail: mtolmasky{at}fullerton.edu.

{dagger} A.J.C.S.B. and F.A.M. have contributed equally to this work.

Antimicrobial Agents and Chemotherapy, May 2006, p. 1903-1907, Vol. 50, No. 5
0066-4804/06/$08.00+0     doi:10.1128/AAC.50.5.1903-1907.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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