This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Falagas, M. E. Articles by Michalopoulos, A. Search for Related Content PubMed PubMed Citation Articles by Falagas, M. E. Articles by Michalopoulos, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, July 2006, p. 2541-2543, Vol. 50, No. 7
0066-4804/06/$08.00+0     doi:10.1128/AAC.00224-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Risk Factors for Isolation of Strains Susceptible Only to Polymyxin among Patients with Pseudomonas aeruginosa Bacteremia

Alfa Institute of Biomedical Sciences, Athens, Greece,¹ Department of Medicine, Henry Dunant Hospital, Athens, Greece,² Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts,³ Critical Care Department, Attikon University Hospital, Athens, Greece,⁴ Intensive Care Unit, Henry Dunant Hospital, Athens, Greece⁵

Received 21 February 2006/ Returned for modification 20 March 2006/ Accepted 10 April 2006

We conducted a case-control study to identify risk factors associated with the isolation of Pseudomonas aeruginosa strains susceptible only to polymyxin from blood by comparing data between 16 patients with blood isolates that were susceptible only to polymyxins and 40 patients with blood isolates that were susceptible to carbapenems. The multivariable analysis showed that exposure to carbapenems was associated with the development of P. aeruginosa bacteremia susceptible only to polymyxin (odds ratio, 9.0; 95% confidence interval, 2.4 to 34.3; P = 0.001).