Previous Article | Next Article 
Antimicrobial Agents and Chemotherapy, August 2006, p. 2880-2882, Vol. 50, No. 8
0066-4804/06/$08.00+0 doi:10.1128/AAC.00186-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
First Detection of the Plasmid-Mediated Class A Carbapenemase KPC-2 in Clinical Isolates of Klebsiella pneumoniae from South America
Maria Virginia Villegas,1
Karen Lolans,2,6
Adriana Correa,1
Carlos Jose Suarez,1
Jaime A. Lopez,3
Marta Vallejo,4
John P. Quinn,2,5,6* the Colombian Nosocomial Resistance Study Group
CIDEIM (International Center for Medical Research and Training), Cali, Colombia,1
John Stroger Hospital, Chicago, Illinois,2
Hospital Pablo Tabon Uribe, Medellin, Colombia,3
Hospital General de Medellin, Medellin, Colombia,4
Rush University Medical Center, Chicago, Illinois,5
Chicago Infectious Disease Research Institute, Chicago, Illinois6
Received 10 February 2006/
Returned for modification 4 April 2006/
Accepted 26 May 2006
The plasmid-mediated class A carbapenemase KPC-2 was isolated from unrelated Klebsiella pneumoniae isolates in Medellin, Colombia. These KPC enzymes are the first from South America and the second isolation outside of the United States. The expanding geographic spread of KPC carbapenemases underscores the importance of clinical recognition of these enzymes.
* Corresponding author. Mailing address: John Stroger Hospital, 1900 W. Polk, Rm 1258, Chicago, IL 60612. Phone: (312) 864-4874. Fax: (312) 864-9522. E-mail: ESBLman{at}yahoo.com.
Antimicrobial Agents and Chemotherapy, August 2006, p. 2880-2882, Vol. 50, No. 8
0066-4804/06/$08.00+0 doi:10.1128/AAC.00186-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
This article has been cited by other articles:
-
Petrella, S., Ziental-Gelus, N., Mayer, C., Renard, M., Jarlier, V., Sougakoff, W.
(2008). Genetic and Structural Insights into the Dissemination Potential of the Extremely Broad-Spectrum Class A {beta}-Lactamase KPC-2 Identified in an Escherichia coli Strain and an Enterobacter cloacae Strain Isolated from the Same Patient in France. Antimicrob. Agents Chemother.
52: 3725-3736
[Abstract]
[Full Text]
-
Woodford, N., Zhang, J., Warner, M., Kaufmann, M. E., Matos, J., MacDonald, A., Brudney, D., Sompolinsky, D., Navon-Venezia, S., Livermore, D. M.
(2008). Arrival of Klebsiella pneumoniae producing KPC carbapenemase in the United Kingdom. J Antimicrob Chemother
0: dkn396v1-4
[Abstract]
[Full Text]
-
Hindiyeh, M., Smollen, G., Grossman, Z., Ram, D., Davidson, Y., Mileguir, F., Vax, M., Ben David, D., Tal, I., Rahav, G., Shamiss, A., Mendelson, E., Keller, N.
(2008). Rapid Detection of blaKPC Carbapenemase Genes by Real-Time PCR. J. Clin. Microbiol.
46: 2879-2883
[Abstract]
[Full Text]
-
Cai, J. C., Zhou, H. W., Zhang, R., Chen, G.-X.
(2008). Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates Possessing the Plasmid-Mediated Carbapenem-Hydrolyzing {beta}-Lactamase KPC-2 in Intensive Care Units of a Chinese Hospital. Antimicrob. Agents Chemother.
52: 2014-2018
[Abstract]
[Full Text]
-
Rasheed, J. K., Biddle, J. W., Anderson, K. F., Washer, L., Chenoweth, C., Perrin, J., Newton, D. W., Patel, J. B.
(2008). Detection of the Klebsiella pneumoniae Carbapenemase Type 2 Carbapenem-Hydrolyzing Enzyme in Clinical Isolates of Citrobacter freundii and K. oxytoca Carrying a Common Plasmid. J. Clin. Microbiol.
46: 2066-2069
[Abstract]
[Full Text]
-
Naas, T., Cuzon, G., Villegas, M.-V., Lartigue, M.-F., Quinn, J. P., Nordmann, P.
(2008). Genetic Structures at the Origin of Acquisition of the {beta}-Lactamase blaKPC Gene. Antimicrob. Agents Chemother.
52: 1257-1263
[Abstract]
[Full Text]
-
Giske, C. G., Monnet, D. L., Cars, O., Carmeli, Y., on behalf of ReAct-Action on Antibiotic Resistance,
(2008). Clinical and Economic Impact of Common Multidrug-Resistant Gram-Negative Bacilli. Antimicrob. Agents Chemother.
52: 813-821
[Full Text]
-
Zhang, R., Yang, L., Cai, J. C., Zhou, H. W., Chen, G.-X.
(2008). High-level carbapenem resistance in a Citrobacter freundii clinical isolate is due to a combination of KPC-2 production and decreased porin expression. J Med Microbiol
57: 332-337
[Abstract]
[Full Text]
-
Mendes, R. E., Bell, J. M., Turnidge, J. D., Yang, Q., Yu, Y., Sun, Z., Jones, R. N.
(2008). Carbapenem-Resistant Isolates of Klebsiella pneumoniae in China and Detection of a Conjugative Plasmid (blaKPC-2 plus qnrB4) and a blaIMP-4 Gene. Antimicrob. Agents Chemother.
52: 798-799
[Full Text]
-
Walther-Rasmussen, J., Hoiby, N.
(2007). Class A carbapenemases. J Antimicrob Chemother
60: 470-482
[Abstract]
[Full Text]
-
Leavitt, A., Navon-Venezia, S., Chmelnitsky, I., Schwaber, M. J., Carmeli, Y.
(2007). Emergence of KPC-2 and KPC-3 in Carbapenem-Resistant Klebsiella pneumoniae Strains in an Israeli Hospital. Antimicrob. Agents Chemother.
51: 3026-3029
[Abstract]
[Full Text]
-
Anderson, K. F., Lonsway, D. R., Rasheed, J. K., Biddle, J., Jensen, B., McDougal, L. K., Carey, R. B., Thompson, A., Stocker, S., Limbago, B., Patel, J. B.
(2007). Evaluation of Methods To Identify the Klebsiella pneumoniae Carbapenemase in Enterobacteriaceae. J. Clin. Microbiol.
45: 2723-2725
[Abstract]
[Full Text]
-
Villegas, M. V., Lolans, K., Correa, A., Kattan, J. N., Lopez, J. A., Quinn, J. P., and the Colombian Nosocomial Resistance Study Grou,
(2007). First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing {beta}-Lactamase. Antimicrob. Agents Chemother.
51: 1553-1555
[Abstract]
[Full Text]
-
Wei, Z.-Q., Du, X.-X., Yu, Y.-S., Shen, P., Chen, Y.-G., Li, L.-J.
(2007). Plasmid-Mediated KPC-2 in a Klebsiella pneumoniae Isolate from China. Antimicrob. Agents Chemother.
51: 763-765
[Abstract]
[Full Text]
Copyright © 2006 by the American Society for Microbiology. All rights reserved.