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Antimicrobial Agents and Chemotherapy, August 2006, p. 2880-2882, Vol. 50, No. 8
0066-4804/06/$08.00+0     doi:10.1128/AAC.00186-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

First Detection of the Plasmid-Mediated Class A Carbapenemase KPC-2 in Clinical Isolates of Klebsiella pneumoniae from South America

Maria Virginia Villegas,1 Karen Lolans,2,6 Adriana Correa,1 Carlos Jose Suarez,1 Jaime A. Lopez,3 Marta Vallejo,4 John P. Quinn,2,5,6* the Colombian Nosocomial Resistance Study Group

CIDEIM (International Center for Medical Research and Training), Cali, Colombia,1 John Stroger Hospital, Chicago, Illinois,2 Hospital Pablo Tabon Uribe, Medellin, Colombia,3 Hospital General de Medellin, Medellin, Colombia,4 Rush University Medical Center, Chicago, Illinois,5 Chicago Infectious Disease Research Institute, Chicago, Illinois6

Received 10 February 2006/ Returned for modification 4 April 2006/ Accepted 26 May 2006

The plasmid-mediated class A carbapenemase KPC-2 was isolated from unrelated Klebsiella pneumoniae isolates in Medellin, Colombia. These KPC enzymes are the first from South America and the second isolation outside of the United States. The expanding geographic spread of KPC carbapenemases underscores the importance of clinical recognition of these enzymes.

* Corresponding author. Mailing address: John Stroger Hospital, 1900 W. Polk, Rm 1258, Chicago, IL 60612. Phone: (312) 864-4874. Fax: (312) 864-9522. E-mail: ESBLman{at}yahoo.com.

Antimicrobial Agents and Chemotherapy, August 2006, p. 2880-2882, Vol. 50, No. 8
0066-4804/06/$08.00+0     doi:10.1128/AAC.00186-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



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