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Antimicrobial Agents and Chemotherapy, January 2007, p. 390-393, Vol. 51, No. 1
0066-4804/07/$08.00+0     doi:10.1128/AAC.00921-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Mosaic Staphylococcal Cassette Chromosome mec Containing Two Recombinase Loci and a New mec Complex, B2{triangledown}

R. Heusser, M. Ender, B. Berger-Bächi, and N. McCallum*

Institute of Medical Microbiology, University of Zurich, Gloriastr. 32, 8006 Zurich, Switzerland

Received 17 July 2006/ Returned for modification 12 October 2006/ Accepted 27 October 2006

A novel staphylococcal cassette chromosome (SCC) mec from a clinical methicillin-resistant Staphylococcus aureus isolate (ST100/CC5) had a mosaic structure, composed of SCC DNA from several different backgrounds. It harbored two complete ccr loci and a new variant of mec complex B, with {Delta}mecR1 interrupted by the aminoglycoside resistance transposon Tn4001.

* Corresponding author. Mailing address: Institute of Medical Microbiology, University of Zurich, 8006 Zurich, Switzerland. Phone: 41 44 634 2694. Fax: 41 44 634 4906. E-mail: mccallum{at}immv.unizh.ch.

{triangledown} Published ahead of print on 6 November 2006.

Antimicrobial Agents and Chemotherapy, January 2007, p. 390-393, Vol. 51, No. 1
0066-4804/07/$08.00+0     doi:10.1128/AAC.00921-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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