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Antimicrobial Agents and Chemotherapy, November 2007, p. 4209-4210, Vol. 51, No. 11
0066-4804/07/$08.00+0     doi:10.1128/AAC.00560-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Identification of 16S rRNA Methylase-Producing Acinetobacter baumannii Clinical Strains in North America

Division of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania,¹ Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, Tokyo, Japan,² University of Queensland, Brisbane, Australia,³ Queensland Health Pathology Services, Royal Brisbane and Women's Hospital, Brisbane, Australia⁴

Received 28 April 2007/ Returned for modification 14 May 2007/ Accepted 20 August 2007

Five highly amikacin-resistant Acinetobacter baumannii isolates were collected at a medical center in Pennsylvania. The aminoglycoside resistance was due to the production of the 16S rRNA methylase ArmA. Two of the isolates coproduced OXA-23 ß-lactamase and were highly resistant to carbapenems as well. The isolates were genetically closely related by pulsed-field gel electrophoresis.

Published ahead of print on 4 September 2007.

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