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Antimicrobial Agents and Chemotherapy, March 2007, p. 1115-1118, Vol. 51, No. 3
0066-4804/07/$08.00+0 doi:10.1128/AAC.00725-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Mosaic Tetracycline Resistance Genes Are Widespread in Human and Animal Fecal Samples
Andrea J. Patterson,
Marco T. Rincon,
Harry J. Flint, and
Karen P. Scott*
Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen, United Kingdom AB21 9SB
Received 12 June 2006/
Returned for modification 21 August 2006/
Accepted 1 November 2006
Mosaic tetracycline resistance genes comprising tet(O), tet(W), and tet(32) sequences were abundant in DNA extracted from pig and human fecal samples, accounting for 78% (50/64) and 46% (37/80) of genes amplified with a tet(O) primer set, respectively, in two samples. The nonmosaic tet(32) gene was isolated from a human saliva bacterium.
* Corresponding author. Mailing address: Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK AB21 9SB. Phone: 44 (0) 1224 712751. Fax: 44 (0) 1224 716687. E-mail: k.scott{at}rowett.ac.uk.
Published ahead of print on 18 December 2006.
Antimicrobial Agents and Chemotherapy, March 2007, p. 1115-1118, Vol. 51, No. 3
0066-4804/07/$08.00+0 doi:10.1128/AAC.00725-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
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