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Antimicrobial Agents and Chemotherapy, March 2007, p. 1115-1118, Vol. 51, No. 3
0066-4804/07/$08.00+0     doi:10.1128/AAC.00725-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Mosaic Tetracycline Resistance Genes Are Widespread in Human and Animal Fecal Samples{triangledown}

Andrea J. Patterson, Marco T. Rincon, Harry J. Flint, and Karen P. Scott*

Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen, United Kingdom AB21 9SB

Received 12 June 2006/ Returned for modification 21 August 2006/ Accepted 1 November 2006

Mosaic tetracycline resistance genes comprising tet(O), tet(W), and tet(32) sequences were abundant in DNA extracted from pig and human fecal samples, accounting for 78% (50/64) and 46% (37/80) of genes amplified with a tet(O) primer set, respectively, in two samples. The nonmosaic tet(32) gene was isolated from a human saliva bacterium.


* Corresponding author. Mailing address: Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK AB21 9SB. Phone: 44 (0) 1224 712751. Fax: 44 (0) 1224 716687. E-mail: k.scott{at}rowett.ac.uk.

{triangledown} Published ahead of print on 18 December 2006.


Antimicrobial Agents and Chemotherapy, March 2007, p. 1115-1118, Vol. 51, No. 3
0066-4804/07/$08.00+0     doi:10.1128/AAC.00725-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




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