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Antimicrobial Agents and Chemotherapy, April 2007, p. 1491-1493, Vol. 51, No. 4
0066-4804/07/$08.00+0     doi:10.1128/AAC.01496-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Activity of Linezolid against 3,251 Strains of Uncommonly Isolated Gram-Positive Organisms: Report from the SENTRY Antimicrobial Surveillance Program{triangledown}

Ronald N. Jones,1,2* Matthew G. Stilwell,1 Patricia A. Hogan,3 and Daniel J. Sheehan3

JMI Laboratories, North Liberty, Iowa,1 Tufts University School of Medicine, Boston, Massachusetts,2 Pfizer Inc, New York, New York3

Received 28 November 2006/ Accepted 22 December 2006

Linezolid was tested against 32 species of uncommonly isolated gram-positive organisms (3,251 strains) by reference MIC methods and found to be highly active (MIC50 range, 0.25 to 2 µg/ml; MIC90 range, 0.25 to 2 µg/ml). Only one isolate (viridans group streptococcus; 0.03% of tested strains) was resistant to linezolid.


* Corresponding author. Mailing address: JMI Laboratories, 345 Beaver Kreek Centre, Suite A, North Liberty, Iowa 52317. Phone: (319) 665-3370. Fax: (319) 655-3371. E-mail: ronald-jones{at}jmilabs.com

{triangledown} Published ahead of print on 8 January 2007.


Antimicrobial Agents and Chemotherapy, April 2007, p. 1491-1493, Vol. 51, No. 4
0066-4804/07/$08.00+0     doi:10.1128/AAC.01496-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.