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Antimicrobial Agents and Chemotherapy, May 2007, p. 1827-1829, Vol. 51, No. 5
0066-4804/07/$08.00+0     doi:10.1128/AAC.01279-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Tn1403, a Multiple-Antibiotic Resistance Transposon Made Up of Three Distinct Transposons{triangledown}

H. W. Stokes,1 Liam D. H. Elbourne,2 and Ruth M. Hall2*

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109,1 School of Molecular and Microbial Biosciences, The University of Sydney, NSW 2006, Australia2

Received 13 October 2006/ Returned for modification 31 December 2006/ Accepted 4 January 2007

Transposon Tn1403 from a clinical Pseudomonas strain is composed of three transposons, including Tn5393c. A related transposon Tn1404* from a plant-associated Pseudomonas strain lacks Tn5393 but includes a transposon carrying the tet(C) tetracycline resistance determinant. These compound transposons illustrate the role of preexisting transposons in generating clusters of antibiotic resistance genes.


* Corresponding author. Mailing address: School of Molecular and Microbial Biosciences, Biochemistry and Microbiology Building G08, The University of Sydney, NSW 2006, Australia. Phone: 61-2-9351-3465. Fax: 61-2-9351-4571. E-mail: ruth.hall{at}mmb.usyd.edu.au

{triangledown} Published ahead of print on 29 January 2007.


Antimicrobial Agents and Chemotherapy, May 2007, p. 1827-1829, Vol. 51, No. 5
0066-4804/07/$08.00+0     doi:10.1128/AAC.01279-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.




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