This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shen, G.-H.
Right arrow Articles by Chen, J.-H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shen, G.-H.
Right arrow Articles by Chen, J.-H.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, May 2007, p. 1849-1851, Vol. 51, No. 5
0066-4804/07/$08.00+0     doi:10.1128/AAC.01551-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of Isepamicin, Other Aminoglycosides, and Capreomycin against Clinical Isolates of Rapidly Growing Mycobacteria in Taiwan{triangledown}

Gwan-Han Shen,1,2 Bo-Da Wu,1 Kun-Ming Wu,3 and Jiann-Hwa Chen2*

Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China,1 Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan, Republic of China,2 Rui-Fu-Shi Medical Laboratory, Taichung, Taiwan, Republic of China3

Received 14 December 2006/ Returned for modification 29 December 2006/ Accepted 1 March 2007

The in vitro activities of isepamicin against 117 Mycobacteria abscessus, 48 Mycobacterium fortuitum, and 20 Mycobacterium chelonae isolates were evaluated by a microdilution test. Isepamicin MIC90s were ≤16 µg/ml for the three species. Isepamicin was as active as amikacin and kanamycin and more active than tobramycin, capreomycin, gentamicin, and streptomycin.

* Corresponding author. Mailing address: Institute of Molecular Biology, National Chung Hsing University, Taichung, Taiwan 402, Republic of China. Phone: 886-04-22851885. Fax: 886-04-22874879. E-mail: jhchen{at}dragon.nchu.edu.tw

{triangledown} Published ahead of print on 12 March 2007.

Antimicrobial Agents and Chemotherapy, May 2007, p. 1849-1851, Vol. 51, No. 5
0066-4804/07/$08.00+0     doi:10.1128/AAC.01551-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»