This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ip, M.
Right arrow Articles by Chan, P. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ip, M.
Right arrow Articles by Chan, P. K.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, June 2007, p. 2192-2194, Vol. 51, No. 6
0066-4804/07/$08.00+0     doi:10.1128/AAC.00139-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Longitudinally Tracking Fluoroquinolone Resistance and Its Determinants in Penicillin-Susceptible and -Nonsusceptible Streptococcus pneumoniae Isolates in Hong Kong, 2000 to 2005{triangledown}

Margaret Ip,* Shirley S. L. Chau, Fang Chi, Edmund S. C. Cheuk, Helen Ma, Raymond W. M. Lai, and Paul K. Chan

Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong

Received 30 January 2007/ Returned for modification 21 February 2007/ Accepted 12 March 2007

Of 1,388 Streptococcus pneumoniae isolates collected from 2000 to 2005, 10.5% had a ciprofloxacin MIC of ≥4.0 µg/ml and 1.6% (range, 0.8% to 4.3% per year) had a levofloxacin MIC of ≥4.0 µg/ml. Molecular characterization indicated that fluoroquinolone resistance occurred independently in our prevalent Spain23F-1 clone, expressing serotypes 23F, 19F, and 14. Rates of resistance to levofloxacin in S. pneumoniae have remained stable at a Hong Kong hospital.

* Corresponding author. Mailing address: Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong. Phone: (852) 2632 1265. Fax: (852) 2647 3227. E-mail: margaretip{at}cuhk.edu.hk

{triangledown} Published ahead of print on 19 March 2007.

Antimicrobial Agents and Chemotherapy, June 2007, p. 2192-2194, Vol. 51, No. 6
0066-4804/07/$08.00+0     doi:10.1128/AAC.00139-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»