Antimicrobial Agents and Chemotherapy, July 2007, p. 2597-2599, Vol. 51, No. 7
0066-4804/07/$08.00+0 doi:10.1128/AAC.00315-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
gyrA and parC Mutations and Associated Quinolone Resistance in Vibrio anguillarum Serotype O2b Strains Isolated from Farmed Atlantic Cod (Gadus morhua) in Norway
D. J. Colquhoun,1*
L. Aarflot,2 and
C. F. Melvold1
National Veterinary Institute, Oslo, Norway,1
North West Fish Health, Gurskøy, Norway2
Received 7 March 2007/
Returned for modification 2 April 2007/
Accepted 7 May 2007
MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of
0.001, 0.06, and 16 µg ml–1. Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.
* Corresponding author. Mailing address: National Veterinary Institute, Section for Fish Health, Ullevaalsveien 68, Oslo 0454, Norway. Phone: 47 23 21 61 41. Fax: 47 23 21 61 01. E-mail: duncan.colquhoun{at}vetinst.no
Published ahead of print on 14 May 2007.
Antimicrobial Agents and Chemotherapy, July 2007, p. 2597-2599, Vol. 51, No. 7
0066-4804/07/$08.00+0 doi:10.1128/AAC.00315-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Copyright © 2007 by the American Society for Microbiology. All rights reserved.