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Antimicrobial Agents and Chemotherapy, July 2007, p. 2597-2599, Vol. 51, No. 7
0066-4804/07/$08.00+0     doi:10.1128/AAC.00315-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

gyrA and parC Mutations and Associated Quinolone Resistance in Vibrio anguillarum Serotype O2b Strains Isolated from Farmed Atlantic Cod (Gadus morhua) in Norway{triangledown}

D. J. Colquhoun,1* L. Aarflot,2 and C. F. Melvold1

National Veterinary Institute, Oslo, Norway,1 North West Fish Health, Gurskøy, Norway2

Received 7 March 2007/ Returned for modification 2 April 2007/ Accepted 7 May 2007

MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of ≤0.001, 0.06, and 16 µg ml–1. Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.

* Corresponding author. Mailing address: National Veterinary Institute, Section for Fish Health, Ullevaalsveien 68, Oslo 0454, Norway. Phone: 47 23 21 61 41. Fax: 47 23 21 61 01. E-mail: duncan.colquhoun{at}vetinst.no

{triangledown} Published ahead of print on 14 May 2007.

Antimicrobial Agents and Chemotherapy, July 2007, p. 2597-2599, Vol. 51, No. 7
0066-4804/07/$08.00+0     doi:10.1128/AAC.00315-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Roig, F. J., Llorens, A., Fouz, B., Amaro, C. (2009). Spontaneous Quinolone Resistance in the Zoonotic Serovar of Vibrio vulnificus. Appl. Environ. Microbiol. 75: 2577-2580 [Abstract] [Full Text]  


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