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Antimicrobial Agents and Chemotherapy, July 2007, p. 2608-2610, Vol. 51, No. 7
0066-4804/07/$08.00+0     doi:10.1128/AAC.00173-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Combined Therapies in a Murine Model of Blastoschizomycosis{triangledown}

Carolina Serena, M. Mar Rodríguez, Marçal Mariné, F. Javier Pastor, and Josep Guarro*

Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain

Received 6 February 2007/ Returned for modification 23 March 2007/ Accepted 6 April 2007

In a murine model of blastoschizomycosis, amphotericin B combined with micafungin, flucytosine or voriconazole did not improve the efficacy of fluconazole. However, such combinations can constitute therapeutic options for those cases where fluconazole fails.

* Corresponding author. Mailing address: Unitat de Microbiologia, Facultat de Medicina, Universitat Rovira i Virgili. Carrer Sant Llorenç, 21.43201 Reus, Spain. Phone: 977-759359. Fax: 977-759322. E-mail: josep.guarro{at}urv.cat

{triangledown} Published ahead of print on 23 April 2007.

Antimicrobial Agents and Chemotherapy, July 2007, p. 2608-2610, Vol. 51, No. 7
0066-4804/07/$08.00+0     doi:10.1128/AAC.00173-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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