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Antimicrobial Agents and Chemotherapy, August 2007, p. 3017-3019, Vol. 51, No. 8
0066-4804/07/$08.00+0     doi:10.1128/AAC.00279-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Novel Complex Class 1 Integron Bearing an ISCR1 Element in an Escherichia coli Isolate Carrying the blaCTX-M-14 Gene{triangledown}

Il Kwon Bae,1 You-Nae Lee,1 Wee Gyo Lee,2 Sang Hee Lee,3 and Seok Hoon Jeong1*

Research Institute for Antimicrobial Resistance and Department of Laboratory Medicine, Kosin University College of Medicine, 602-030, 34 Amnam-Dong, Suh-Gu, Busan,1 Department of Laboratory Medicine, Ajou University School of Medicine, 442-749, San 5 Wonchun-Dong, Youngtong-Gu, Suwon,2 Department of Biological Sciences, Myongji University, 449-728, San 38-2 Nam-Dong, Yongin, Gyeonggido, Korea3

Received 24 February 2007/ Returned for modification 20 April 2007/ Accepted 8 May 2007

This work identifies an ISCR1-related blaCTX-M-14 gene, which has never been reported before, from a clinical isolate of Escherichia coli. The blaCTX-M-14 gene was preceded by an ISCR1 element that was followed by a class 1 integron containing three different insert gene cassettes, i.e., dfrA12, orfF, and aadA2.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Kosin University College of Medicine, 602-030, 34 Amnam-Dong, Suh-Gu, Busan, Republic of Korea. Phone: 82-51-990-6373. Fax: 82-51-990-3034. E-mail: kscpjsh{at}ns.kosinmed.or.kr

{triangledown} Published ahead of print on 21 May 2007.

Antimicrobial Agents and Chemotherapy, August 2007, p. 3017-3019, Vol. 51, No. 8
0066-4804/07/$08.00+0     doi:10.1128/AAC.00279-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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