This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Swarup, V.
Right arrow Articles by Basu, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Swarup, V.
Right arrow Articles by Basu, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, September 2007, p. 3367-3370, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00041-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Antiviral and Anti-Inflammatory Effects of Rosmarinic Acid in an Experimental Murine Model of Japanese Encephalitis{triangledown}

Vivek Swarup, Joydeep Ghosh, Soumya Ghosh, Amit Saxena, and Anirban Basu*

National Brain Research Centre, Manesar, Haryana, India

Received 12 January 2007/ Returned for modification 8 March 2007/ Accepted 1 June 2007

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

* Corresponding author. Mailing address: National Brain Research Centre, Manesar, Haryana-122050, India. Phone: 91-124-2338921. Fax: 91-124-2338910. E-mail: anirban{at}nbrc.res.in

{triangledown} Published ahead of print on 18 June 2007.

Antimicrobial Agents and Chemotherapy, September 2007, p. 3367-3370, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00041-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Swarup, V., Ghosh, J., Mishra, M. K., Basu, A. (2008). Novel strategy for treatment of Japanese encephalitis using arctigenin, a plant lignan. J Antimicrob Chemother 61: 679-688 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»