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Antimicrobial Agents and Chemotherapy, September 2007, p. 3391-3393, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00473-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Haemophilus ducreyi Is Resistant to Human Antimicrobial Peptides{triangledown}

Kristy L. B. Mount, Carisa A. Townsend, and Margaret E. Bauer*

Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana

Received 5 April 2007/ Returned for modification 15 June 2007/ Accepted 2 July 2007

We examined the susceptibility of Haemophilus ducreyi to antimicrobial peptides likely to be encountered in vivo during human infection. H. ducreyi was significantly more resistant than Escherichia coli to the bactericidal effects of all peptides tested. Class I and II H. ducreyi strains exhibited similar levels of resistance to antimicrobial peptides.

* Corresponding author. Mailing address: 635 Barnhill Dr., Room MS 420, Indianapolis, IN 46202-5124. Phone: (317) 274-8143. Fax: (317) 274-4090. E-mail: mebauer{at}iupui.edu

{triangledown} Published ahead of print on 9 July 2007.

Antimicrobial Agents and Chemotherapy, September 2007, p. 3391-3393, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00473-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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