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Antimicrobial Agents and Chemotherapy, September 2007, p. 3394-3396, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00358-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Tick Acquisition of Ehrlichia canis from Dogs Treated with Doxycycline Hyclate{triangledown}

John J. Schaefer,1,2 Glen R. Needham,2 William G. Bremer,1 Yasuko Rikihisa,3 S. A. Ewing,4 and R. W. Stich5*

Departments of Veterinary Preventive Medicine,1 Entomology,2 Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210,3 Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, Oklahoma 74078,4 Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri 652115

Received 16 March 2007/ Returned for modification 8 May 2007/ Accepted 20 June 2007

Doxycycline generally alleviates clinical monocytic ehrlichiosis, but its efficacy in the control of monocytotropic ehrlichial pathogens requires further investigation. In this study, Ehrlichia canis was detected in dogs treated with doxycycline for 14 days and in ticks fed on these dogs, suggesting that treated dogs can remain reservoirs for E. canis.

* Corresponding author. Mailing address: Department of Veterinary Pathobiology, University of Missouri, 210 Connaway Hall, Columbia, MO 65211. Phone: (573) 882-3148. Fax: (573) 884-5414. E-mail: stichrw{at}missouri.edu

{triangledown} Published ahead of print on 2 July 2007.

Antimicrobial Agents and Chemotherapy, September 2007, p. 3394-3396, Vol. 51, No. 9
0066-4804/07/$08.00+0     doi:10.1128/AAC.00358-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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