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Antimicrobial Agents and Chemotherapy, November 2008, p. 4153-4154, Vol. 52, No. 11
0066-4804/08/$08.00+0     doi:10.1128/AAC.00710-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Recovery of a Functional Class 2 Integron from an Escherichia coli Strain Mediating a Urinary Tract Infection{triangledown}

Carolina Márquez,1,4 Maurizio Labbate,2 Ana J. Ingold,1 Piklu Roy Chowdhury,2 Maria S. Ramírez,3 Daniela Centrón,3 Graciela Borthagaray,4 and H. W. Stokes2*

Cátedra de Microbiología, Instituto de Química Biológica, Facultad de Ciencias,1 Cátedra de Microbiología, Facultad de Química, UDELAR, Montevideo, Uruguay,4 Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109, Australia,2 Departmento de Microbiología, Parasitología e Immunología, Facultad de Medicina de la Universidad de Buenos Aires, Buenos Aires, Argentina3

Received 29 May 2008/ Returned for modification 9 August 2008/ Accepted 6 September 2008

A class 2 integron was found in an Escherichia coli isolate mediating a urinary tract infection. Unlike other class 2 integrons from pathogens, the encoded IntI2 protein was functional. The integron possessed a dfrA14 cassette, and a second novel cassette in which a lipoprotein signal peptidase gene is predicted.

* Corresponding author. Present address: Department of Medical and Molecular Biosciences, Faculty of Science, University of Technology, Sydney, P.O. Box 123, Broadway, NSW 2007, Australia. Phone: (612) 9514 2232. Fax: (612) 9514 8206. E-mail: hatch.stokes{at}uts.edu.au

{triangledown} Published ahead of print on 15 September 2008.

Antimicrobial Agents and Chemotherapy, November 2008, p. 4153-4154, Vol. 52, No. 11
0066-4804/08/$08.00+0     doi:10.1128/AAC.00710-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Larouche, A., Roy, P. H. (2009). Analysis by Mutagenesis of a Chromosomal Integron Integrase from Shewanella amazonensis SB2BT. J. Bacteriol. 191: 1933-1940 [Abstract] [Full Text]  


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