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Antimicrobial Agents and Chemotherapy, February 2008, p. 732-734, Vol. 52, No. 2
0066-4804/08/$08.00+0     doi:10.1128/AAC.01012-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vitro Antifungal Susceptibilities of Five Species of Sporothrix{triangledown}

Rita Marimon, Carolina Serena, Josepa Gené, Josep Cano, and Josep Guarro*

Unitat de Microbiologia, Facultat de Medicina i Ciéncies de la Salut, Universitat Rovira i Virgili, Reus, Spain

Received 1 August 2007/ Returned for modification 10 October 2007/ Accepted 10 November 2007

Ninety-two isolates belonging to five species of the Sporothrix schenckii complex were tested in vitro against 12 antifungal agents, using a reference microdilution method. There were significant differences among the species; Sporothrix brasiliensis was the species that showed the best response to antifungals, and S. mexicana had the worst response. In general, terbinafine was the most active drug, followed by ketoconazole and posaconazole.

* Corresponding author. Mailing address: Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Carrer Sant Llorenç, 21.43201 Reus, Spain. Phone: 34-977-759359. Fax: 34-977-759322. E-mail: josep.guarro{at}urv.cat

{triangledown} Published ahead of print on 26 November 2007.

Antimicrobial Agents and Chemotherapy, February 2008, p. 732-734, Vol. 52, No. 2
0066-4804/08/$08.00+0     doi:10.1128/AAC.01012-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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