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Antimicrobial Agents and Chemotherapy, April 2008, p. 1549-1550, Vol. 52, No. 4
0066-4804/08/$08.00+0     doi:10.1128/AAC.00148-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vivo Therapeutic Effect of Gatifloxacin on BALB/c Mice Infected with Nocardia brasiliensis{triangledown}

Alejandra Daw-Garza,1 Oliverio Welsh,1 Salvador Said-Fernández,3 Hector Gerardo Lozano-Garza,3 Noemi Waksman de Torres,2 Norma Cavazos Rocha,2 Jorge Ocampo-Candiani,1 and Lucio Vera-Cabrera1*

Servicio de Dermatología, Hospital Universitario "José E. González," Monterrey, N.L,1 Departamento de Química Analítica Facultad de Medicina, UANL, Monterrey, N.L,2 Centro de Investigación Biomédica del Noreste, IMSS, Monterrey, N.L., México3

Received 2 February 2008/ Accepted 6 February 2008

In the present work, we evaluated the effect of gatifloxacin on the evolution of experimental murine infection with Nocardia brasiliensis using linezolid as a control. Gatifloxacin was injected subcutaneously at 100 mg/kg body weight every 8 h for 4 weeks. This compound was equally as efficient as linezolid in reducing the production of lesions.

* Corresponding author. Mailing address: Servicio de Dermatología, Hospital Universitario, U.A.N.L., Madero y Gonzalitos, Colonia Mitras Centro, C.P. 64460, Monterrey, N.L., México. Phone: 5281 8348 0383. Fax: 5281 8348 44 07. E-mail: luvera_99{at}yahoo.com

{triangledown} Published ahead of print on 19 February 2008.

Antimicrobial Agents and Chemotherapy, April 2008, p. 1549-1550, Vol. 52, No. 4
0066-4804/08/$08.00+0     doi:10.1128/AAC.00148-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Chacon-Moreno, B. E., Welsh, O., Cavazos-Rocha, N., de la Luz Salazar-Cavazos, M., Garza-Lozano, H. G., Said-Fernandez, S., Ocampo-Candiani, J., Vera-Cabrera, L. (2009). Efficacy of Ciprofloxacin and Moxifloxacin against Nocardia brasiliensis In Vitro and in an Experimental Model of Actinomycetoma in BALB/c Mice. Antimicrob. Agents Chemother. 53: 295-297 [Abstract] [Full Text]  


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