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Antimicrobial Agents and Chemotherapy, April 2008, p. 1551-1552, Vol. 52, No. 4
0066-4804/08/$08.00+0     doi:10.1128/AAC.01580-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Antibiotic Susceptibility of Invasive Haemophilus influenzae Strains in Canada{triangledown}

Michelle L. Sill and Raymond S. W. Tsang*

Vaccine Preventable Bacterial Diseases, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada

Received 7 December 2007/ Returned for modification 11 January 2008/ Accepted 17 January 2008

Canadian invasive Haemophilus influenzae isolates from 1990 to 2006 were examined for antibiotic susceptibility: 42 strains (17.8%) were resistant to ampicillin by β-lactamase production, 5.5% were β-lactamase negative ampicillin intermediate, and 2.5% were intermediate to only the 2-µg ampicillin disk. An increase in β-lactamase-negative ampicillin-intermediate strains has been found.


* Corresponding author. Mailing address: National Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, Canada R3E 3R2. Phone: (204) 789-6020. Fax: (204) 789-2018. E-mail: raymond_tsang{at}phac-aspc.gc.ca

{triangledown} Published ahead of print on 28 January 2008.


Antimicrobial Agents and Chemotherapy, April 2008, p. 1551-1552, Vol. 52, No. 4
0066-4804/08/$08.00+0     doi:10.1128/AAC.01580-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.




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