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Antimicrobial Agents and Chemotherapy, May 2008, p. 1859-1861, Vol. 52, No. 5
0066-4804/08/$08.00+0     doi:10.1128/AAC.01646-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Secretion of E,E-Farnesol and Biofilm Formation in Eight Different Candida Species{triangledown}

K. Weber,1 R. Sohr,2 B. Schulz,1 M. Fleischhacker,1 and M. Ruhnke1*

Division of Oncology and Hematology, Department of Medicine,1 Institute of Pharmacology, Charité—Universitätsmedizin Berlin, Berlin, Germany2

Received 21 December 2007/ Returned for modification 20 January 2008/ Accepted 2 March 2008

Production of E,E-farnesol (FOH) and biofilm formation were studied under various conditions in 56 strains of eight Candida spp. FOH production differed significantly not only between Candida spp. but within Candida albicans strains as well. FOH concentrations and biofilm formation were the highest for C albicans.

* Corresponding author. Mailing address: Charité—Universitätsmedizin Berlin, Department of Medicine, Division of Oncology and Hematology, Charitéplatz 1, 10117 Berlin, Germany. Phone: 49 (30) 450 51 30 36. Fax: 49 (30) 450 51 39 37. E-mail: markus.ruhnke{at}charite.de

{triangledown} Published ahead of print on 10 March 2008.

Antimicrobial Agents and Chemotherapy, May 2008, p. 1859-1861, Vol. 52, No. 5
0066-4804/08/$08.00+0     doi:10.1128/AAC.01646-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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