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Antimicrobial Agents and Chemotherapy, May 2008, p. 1865-1867, Vol. 52, No. 5
0066-4804/08/$08.00+0     doi:10.1128/AAC.00017-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Detection of New arr-4 and arr-5 Gene Cassettes in Clinical Pseudomonas aeruginosa and Klebsiella pneumoniae Strains from Brazil{triangledown}

Érica Lourenço da Fonseca,1* Fernanda dos Santos Freitas,1 José Carlos de Amorim,2 and Ana Carolina Paulo Vicente1

Laboratório de Genética Molecular de Microrganismos, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil,1 Laboratório de Microbiologia, Hospital Estadual Getúlio Vargas, Rio de Janeiro, Brazil2

Received 4 January 2008/ Returned for modification 12 January 2008/ Accepted 16 February 2008

New arr alleles emerged in class 1 integrons from a clinical Pseudomonas aeruginosa strain (arr-4) and four Klebsiella pneumoniae strains (arr-5) in Brazil/American continent. arr-4 was preceded by aacA7-catB3, whereas arr-5 was the unique cassette. The putative proteins shared 75% (Arr-5) and 78% (Arr-4) identities with Arr-2.

* Corresponding author. Mailing address: Instituto Oswaldo Cruz/FIOCRUZ, Laboratório de Genética Molecular de Microrganismos, Avenida Brasil 4365, P.O. Box 926, CEP 21045-900, Manguinhos, Rio de Janeiro, Brazil. Phone: 55-21-3865-8168. Fax: 55-21-2260-4282. E-mail: ericafon{at}ioc.fiocruz.br

{triangledown} Published ahead of print on 25 February 2008.

Antimicrobial Agents and Chemotherapy, May 2008, p. 1865-1867, Vol. 52, No. 5
0066-4804/08/$08.00+0     doi:10.1128/AAC.00017-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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