This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ruan, S.-Y.
Right arrow Articles by Hsueh, P.-R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ruan, S.-Y.
Right arrow Articles by Hsueh, P.-R.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, August 2008, p. 2919-2922, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.00323-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

In Vitro Susceptibilities of Invasive Isolates of Candida Species: Rapid Increase in Rates of Fluconazole Susceptible-Dose Dependent Candida glabrata Isolates{triangledown}

Sheng-Yuan Ruan,1 Chen-Chen Chu,2 and Po-Ren Hsueh3,4*

Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan,1 Department of Pharmacology, National Taiwan University Hospital, Taipei, Taiwan,2 Departments of Internal Medicine,3 Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan4

Received 10 March 2008/ Returned for modification 9 April 2008/ Accepted 24 April 2008

Voriconazole, posaconazole, caspofungin, micafungin, and anidulafungin demonstrated potent in vitro activities against 286 invasive Candida isolates. Analysis of the fluconazole susceptibilities of 204 bloodstream Candida glabrata isolates revealed a rapid shift from susceptible (64% in 1999 to 2001 to 19% in 2007) to susceptible-dose dependent (27% in 1999 to 2001 and 75% in 2007).

* Corresponding author. Mailing address: Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7, Chung-Shan South Road, Taipei 100, Taiwan. Phone: 886-2-3123456, ext. 5355. Fax: 886-2-23224263. E-mail: hsporen{at}ntu.edu.tw

{triangledown} Published ahead of print on 5 May 2008.

Antimicrobial Agents and Chemotherapy, August 2008, p. 2919-2922, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.00323-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»