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Antimicrobial Agents and Chemotherapy, August 2008, p. 2984-2987, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.01634-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

blaIMP-4 in Different Genetic Contexts in Enterobacteriaceae Isolates from Australia{triangledown}

Björn A. Espedido, Sally R. Partridge, and Jonathan R. Iredell*

Centre for Infectious Diseases & Microbiology, University of Sydney, Westmead Hospital, Westmead, New South Wales 2145, Australia

Received 20 December 2007/ Returned for modification 19 February 2008/ Accepted 8 May 2008

The IMP-4 metallo-β-lactamase, originally recognized in Acinetobacter spp. from Hong Kong, more recently appeared simultaneously in isolates of the family Enterobacteriaceae from Sydney and Melbourne, Australia. The blaIMP-4-qacG2-aacA4-catB3 cassette array was found in isolates from both cities, but in different wider genetic contexts and on different plasmids, suggesting movement of this array by homologous recombination.

* Corresponding author. Mailing address: CIDM, Level 3 ICPMR Building, Westmead Hospital, Westmead, NSW 2145, Australia. Phone: 612-9845-6255. Fax: 612-9891-5317. E-mail: jon.iredell{at}swahs.health.nsw.gov.au

{triangledown} Published ahead of print on 19 May 2008.

Antimicrobial Agents and Chemotherapy, August 2008, p. 2984-2987, Vol. 52, No. 8
0066-4804/08/$08.00+0     doi:10.1128/AAC.01634-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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  • Zong, Z., Partridge, S. R., Thomas, L., Iredell, J. R. (2008). Dominance of blaCTX-M within an Australian Extended-Spectrum {beta}-Lactamase Gene Pool. Antimicrob. Agents Chemother. 52: 4198-4202 [Abstract] [Full Text]  


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