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Antimicrobial Agents and Chemotherapy, January 2009, p. 303-305, Vol. 53, No. 1
0066-4804/09/$08.00+0     doi:10.1128/AAC.00901-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

International Interlaboratory Proficiency Testing Program for Measurement of Azole Antifungal Plasma Concentrations{triangledown}

Roger J. M. Brüggemann,1,2* Daan J. Touw,3,4 Rob E. Aarnoutse,1,2 Paul E. Verweij,2,5 and David M. Burger1,2

Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands,1 Nijmegen University Centre for Infectious Diseases, Nijmegen, The Netherlands,2 Department of Hospital Pharmacy, The Hague Central Hospital Pharmacy, The Hague, The Netherlands,3 Association for Quality Assessment in Therapeutic Drug Monitoring and Clinical Toxicology (KKGT), The Hague, The Netherlands,4 Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands5

Received 8 July 2008/ Returned for modification 14 August 2008/ Accepted 4 November 2008

An international interlaboratory proficiency testing program for the measurement of antifungal drugs was initiated in 2007. This first round was limited to azole antifungals: fluconazole, itraconazole and hydroxyitraconazole, voriconazole, and posaconazole. The results demonstrate the need for and utility of an ongoing proficiency testing program to further improve the analytical methods for routine patient management and clinical research.

* Corresponding author. Mailing address: Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Nijmegen University Centre for Infectious Diseases, PO BOX 9101, 6500 HB Nijmegen, The Netherlands. Phone: 31243616405. Fax: 31243668755. E-mail: R.Bruggemann{at}akf.umcn.nl

{triangledown} Published ahead of print on 17 November 2008.

Antimicrobial Agents and Chemotherapy, January 2009, p. 303-305, Vol. 53, No. 1
0066-4804/09/$08.00+0     doi:10.1128/AAC.00901-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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