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Antimicrobial Agents and Chemotherapy, October 2009, p. 4508-4510, Vol. 53, No. 10
0066-4804/09/$08.00+0     doi:10.1128/AAC.00721-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Susceptibility of Urinary Tract Bacteria to Fosfomycin{triangledown}

Sofia Maraki,1 George Samonis,2 Petros I. Rafailidis,3,4 Evridiki K. Vouloumanou,3 Emmanuel Mavromanolakis,5 and Matthew E. Falagas3,4,6*

Department of Clinical Microbiology, University Hospital of Heraklion, Heraklion, Crete, Greece,1 Department of Medicine, University Hospital of Heraklion, Heraklion, Crete, Greece,2 Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece,3 Department of Medicine, Henry Dunant Hospital, Athens, Greece,4 Department of Urology, University Hospital of Heraklion, Crete, Greece,5 Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts6

Received 28 May 2009/ Returned for modification 6 July 2009/ Accepted 3 August 2009

We evaluated the in vitro activity of fosfomycin against urinary isolates in a region in Greece that exhibits considerable antimicrobial resistance by evaluating retrospectively relevant susceptibility data retrieved from the microbiological library of the University Hospital of Heraklion, Crete, Greece. We examined 578 urinary isolates. In total, 516 (89.2%) were susceptible to fosfomycin; 415 isolates were gram negative, and 101 isolates were gram positive. Fosfomycin appears to exhibit good levels of in vitro activity against the examined urinary isolates.

* Corresponding author. Mailing address: Alfa Institute of Biomedical Sciences (AIBS), 9 Neapoleos Street, 151 23 Marousi, Athens, Greece. Phone: 30 (694) 611-0000. Fax: 30 (210) 683-9605. E-mail: m.falagas{at}aibs.gr

{triangledown} Published ahead of print on 17 August 2009.

Antimicrobial Agents and Chemotherapy, October 2009, p. 4508-4510, Vol. 53, No. 10
0066-4804/09/$08.00+0     doi:10.1128/AAC.00721-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Endimiani, A., Patel, G., Hujer, K. M., Swaminathan, M., Perez, F., Rice, L. B., Jacobs, M. R., Bonomo, R. A. (2010). In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin. Antimicrob. Agents Chemother. 54: 526-529 [Abstract] [Full Text]  


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