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Antimicrobial Agents and Chemotherapy, October 2009, p. 4511-4513, Vol. 53, No. 10
0066-4804/09/$08.00+0     doi:10.1128/AAC.00784-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Regional Dissemination of KPC-Producing Klebsiella pneumoniae{triangledown}

Brandon Kitchel,1* Daniel R. Sundin,2 and Jean B. Patel1

Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia,1 Spectrum Health, Grand Rapids, Michigan2

Received 12 June 2009/ Returned for modification 7 July 2009/ Accepted 7 August 2009

Production of a Klebsiella pneumoniae carbapenemase (KPC) is the most common mechanism of carbapenem resistance in the United States; however, until now, KPC-producing isolates have not been found in western Michigan. Molecular typing of two KPC-producing K. pneumoniae isolates from Michigan showed their similarity to other Midwestern isolates. They were also unrelated to the dominant sequence type observed throughout the United States, multilocus sequence type 258. This could represent regional dissemination of another KPC-producing K. pneumoniae strain.


* Corresponding author. Mailing address: Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd., Atlanta, GA 30333. Phone: (404) 639-0208. Fax: (404) 639-1381. E-mail: bkitchel{at}cdc.gov

{triangledown} Published ahead of print on 17 August 2009.


Antimicrobial Agents and Chemotherapy, October 2009, p. 4511-4513, Vol. 53, No. 10
0066-4804/09/$08.00+0     doi:10.1128/AAC.00784-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.