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Antimicrobial Agents and Chemotherapy, November 2009, p. 4938-4939, Vol. 53, No. 11
0066-4804/09/$08.00+0     doi:10.1128/AAC.00724-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibilities of Mycoplasma genitalium Strains Examined by Broth Dilution and Quantitative PCR{triangledown}

Ryoichi Hamasuna,1,2* Jørgen Skov Jensen,3 and Yukio Osada2

Department of Urology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan,1 Division of Urology, Department of Surgery, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan,2 Mycoplasma Laboratory, Statens Serum Institut, DK-2300 Copenhagen, Denmark3

Received 28 May 2009/ Returned for modification 6 July 2009/ Accepted 1 September 2009

Only limited information regarding the antimicrobial susceptibilities of Mycoplasma genitalium is available because of difficulties in isolating M. genitalium strains from clinical specimens. Antimicrobial susceptibilities of 15 clinical isolates, 7 ATCC strains, and an early passage of the M30 strain were examined by the broth dilution method. Azithromycin, clarithromycin, sitafloxacin, and moxifloxacin were the most active drugs against M. genitalium, and their MIC90s were 0.002, 0.008, 0.125, and 0.125 mg/liter, respectively.

* Corresponding author. Mailing address: Department of Urology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka 807-8555, Japan. Phone: 81 93 691 7446. Fax: 81 93 603 8724. E-mail: hamaryo{at}med.uoeh-u.ac.jp

{triangledown} Published ahead of print on 8 September 2009.

Antimicrobial Agents and Chemotherapy, November 2009, p. 4938-4939, Vol. 53, No. 11
0066-4804/09/$08.00+0     doi:10.1128/AAC.00724-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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