This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Girlich, D.
Right arrow Articles by Nordmann, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Girlich, D.
Right arrow Articles by Nordmann, P.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, February 2009, p. 832-834, Vol. 53, No. 2
0066-4804/09/$08.00+0     doi:10.1128/AAC.01007-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

CTX-M Expression and Selection of Ertapenem Resistance in Klebsiella pneumoniae and Escherichia coli{triangledown}

Delphine Girlich, Laurent Poirel, and Patrice Nordmann*

Service de Bactériologie-Virologie, INSERM U914 "Emerging Resistance to Antibiotics," Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine et Université Paris Sud, 94275 K.-Bicêtre, France

Received 28 July 2008/ Returned for modification 9 October 2008/ Accepted 14 November 2008

In vitro selection of mutants with decreased susceptibility to ertapenem was performed using Escherichia coli and Klebsiella pneumoniae clinical strains producing either the blaCTX-M-2, blaCTX-M-3, blaCTX-M-9, or blaCTX-M-15 gene. Frequencies of mutants with decreased susceptibilities to ertapenem were similar for all β-lactamases expressed.

* Corresponding author. Mailing address: Hôpital de Bicêtre, Service de Bactériologie-Virologie, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre, France. Phone: 33-1-45-21-36-32. Fax: 33-1-45-21-63-40. E-mail: nordmann.patrice{at}bct.aphp.fr

{triangledown} Published ahead of print on 24 November 2008.

Antimicrobial Agents and Chemotherapy, February 2009, p. 832-834, Vol. 53, No. 2
0066-4804/09/$08.00+0     doi:10.1128/AAC.01007-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Rodriguez-Martinez, J.-M., Poirel, L., Nordmann, P. (2009). Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 53: 4783-4788 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»