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Antimicrobial Agents and Chemotherapy, April 2009, p. 1693-1697, Vol. 53, No. 4
0066-4804/09/$08.00+0     doi:10.1128/AAC.01313-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

A blaVEB-1 Variant, blaVEB-6, Associated with Repeated Elements in a Complex Genetic Structure{triangledown}

Zhiyong Zong,1,2 Sally R. Partridge,1* and Jonathan R. Iredell1

Centre for Infectious Diseases and Microbiology, Westmead Hospital, the University of Sydney, Westmead, NSW, Australia,1 Department of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China2

Received 1 October 2008/ Returned for modification 23 November 2008/ Accepted 3 January 2009

blaVEB-6 was found on the Proteus mirabilis chromosome in a context similar to those of blaVEB-1a and blaVEB-1b, in a truncated gene cassette flanked by 135-bp elements and duplications of the 3'-conserved segment of class 1 integrons. A linked aacA4-aadB-dfrA1-orfC cassette array includes components of Tn1331, illustrating the complex mosaicism of multiresistance regions.

* Corresponding author. Mailing address: CIDM, Level 3 ICPMR Building, Westmead Hospital, Westmead, NSW 2145, Australia. Phone: 61-2-9845-6278. Fax: 61-2-9891-5317. E-mail: sally.partridge{at}swahs.health.nsw.gov.au

{triangledown} Published ahead of print on 12 January 2009.

Antimicrobial Agents and Chemotherapy, April 2009, p. 1693-1697, Vol. 53, No. 4
0066-4804/09/$08.00+0     doi:10.1128/AAC.01313-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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